3-D Chromatin Remodeling &
Replication
'single molecule to whole genome'
Copyright 2023 @Taneja lab
Our lab investigates local and spatial re-organization of chromatinized replication forks in response to replication stress. We use a combination of super-resolution
imaging, genomics and proteomics based approaches to understand the complex mechanisms of chromatin regulation in maintaining replication fork stability in normal as well as cancer cells.
LATEST LAB NEWS:
-
We secured Oncode Technology Development Funding to develop a clinical-grade ChromStretch Assay for predicting therapy response in tumor cells - Dec
- Our lab received an EU-HORIZON Marie Skłodowska-Curie Fellowship for a new postdoc!
Stay tuned on our latest research in upcoming meetings
We are invited at following events, please register by clicking on the meeting link below:
2024:
.3rd Subhash Mukhopadhyay Symposium 2024
.EMBO Workshop: Evolution and diversity of the DNA damage response 2024
.Seminar series organized by the IMCR, University of Zurich, Switzerland 2024
.Seminar series organized by the CS&D Utrecht Medical Center Utrecht, Netherlands 2024
.EMBO Workshop: Chromatin dynamics and nuclear organization in genome maintenance 2024
.EMBO | EMBL Symposium: DNA replication: from basic biology to disease 2024
2025:
. 4R-RTG I R-loop Club with Dr. Nitika Taneja - Joint event with SFB1361 2025
. Challenges in DNA Repair I Workshop @ Lorentz Center Leiden 2025
. Keystone Symposia: DNA Replication Gaps, Cancer and Disease, Daejeon, South Korea, 2025
. Fusion Conference: 2ndBalancing Genome Fidelity & Plasticity Conference, Lisbon, Portugal, 2025
. Birmingham Center for Genome Biology (BCGB Conference), Birmingham, UK, 2025
. Seminar series at Genome Integrity and Cancers Department at Gustave Roussy, Paris, France, 2025
. Seminar at IFOM, The AIRC Institute of Molecular Oncology, Milan, Italy, 2025
2026:
. The 22nd Aaxia Telangiectasia Workshop (ATW), 2026
. GiiN (Genome Integrity Italian Network) webinar, 2026
. 12th Quinquennial Conference on Responses to DNA damage, Egmond aan Zee, The Netherlands, 2026
. Keystone Symposia: DNA Replication Gaps, Cancer and Disease, Daejeon, South Korea, 2025
. At the Intersection of DNA Replication and Genome Maintenance: From Basic Mechanisms to Therapeutic Opportunities- ICGEB, Trieste, Italy, 2026
 2020-2022 Pawe%c5%82 Kuna Permission is hereby granted%2c free of charge%2c to any person obtaining a copy of this software and associated documentation files (the 'Software')%2c to deal in the Software without restriction%2c including without limitation the rights to use%2c copy%2c modify%2c merge%2c publish%2c distribute%2c sublicense%2c and/or sell copies of the Software%2c and to permit persons to whom the Software is furnished to do so%2c subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED 'AS IS'%2c WITHOUT WARRANTY OF ANY KIND%2c EXPRESS OR IMPLIED%2c INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY%2c FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM%2c DAMAGES OR OTHER LIABILITY%2c WHETHER IN AN ACTION OF CONTRACT%2c TORT OR OTHERWISE%2c ARISING FROM%2c OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. %3c/schema:copyrightNotice%3e%3c/rdf:Description%3e%3c/rdf:RDF%3e%3c/metadata%3e%3cpath stroke='none' d='M0 0h24v24H0z' fill='none'/%3e%3cpath d='M3 12h1m8 -9v1m8 8h1m-15.4 -6.4l.7 .7m12.1 -.7l-.7 .7'/%3e%3cpath d='M9 16a5 5 0 1 1 6 0a3.5 3.5 0 0 0 -1 3a2 2 0 0 1 -4 0a3.5 3.5 0 0 0 -1 -3'/%3e%3cline x1='9.7' y1='17' x2='14.3' y2='17'/%3e%3c/svg%3e)
Funding
 2020-2022 Pawe%c5%82 Kuna Permission is hereby granted%2c free of charge%2c to any person obtaining a copy of this software and associated documentation files (the 'Software')%2c to deal in the Software without restriction%2c including without limitation the rights to use%2c copy%2c modify%2c merge%2c publish%2c distribute%2c sublicense%2c and/or sell copies of the Software%2c and to permit persons to whom the Software is furnished to do so%2c subject to the following conditions: The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software. THE SOFTWARE IS PROVIDED 'AS IS'%2c WITHOUT WARRANTY OF ANY KIND%2c EXPRESS OR IMPLIED%2c INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY%2c FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM%2c DAMAGES OR OTHER LIABILITY%2c WHETHER IN AN ACTION OF CONTRACT%2c TORT OR OTHERWISE%2c ARISING FROM%2c OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE. %3c/schema:copyrightNotice%3e%3c/rdf:Description%3e%3c/rdf:RDF%3e%3c/metadata%3e%3cpath stroke='none' d='M0 0h24v24H0z' fill='none'/%3e%3ccircle cx='9' cy='7' r='4'/%3e%3cpath d='M3 21v-2a4 4 0 0 1 4 -4h4a4 4 0 0 1 4 4v2'/%3e%3cpath d='M16 3.13a4 4 0 0 1 0 7.75'/%3e%3cpath d='M21 21v-2a4 4 0 0 0 -3 -3.85'/%3e%3c/svg%3e)
